ties / family ties / relatives and in-laws / dependents / encumbrances

annoyance / nuisance / bother / trouble / encumbrances

trouble / annoyance / bother / nuicance

course of events / passage / course / pass / elapse / elapsing / progress / progressing / go by / passing / going by

system / series

sequence

subsidiary (company)

policy of granting franchises

having cramps / having twitches / having spasms / having convulsions / <<entire body>> having seizures / <<small>> having a tic